Amenorrhea in adolescents

Gisella Newbery, Mekala Neelakantan, Maria Demma Cabral, Hatim Omar


Amenorrhea is the absence of spontaneous menstruation in women of reproductive age. Understanding the normal menstrual physiology and regulatory processes is important in differentiating etiologies when evaluating amenorrhea. In adolescents, amenorrhea may warrant investigation, and pregnancy should always be ruled out. In young female adolescents, amenorrhea can be the presenting symptom of different conditions such as polycystic ovary syndrome, eating disorders, or female athlete triad. It is particularly important that menstrual cycle disorders be appropriately analyzed due to potentially serious and detrimental consequences of amenorrhea. Early diagnosis is essential to yielding more favorable outcomes. If not addressed early, future negative implications may ensue.